Mouse ErbB4-ELISA

Mouse ErbB4-ELISA

Objective: ERBB4

Reactivity: Mouse

Detection method: Colorimetric

Request: ELISA

Characteristics

Mus musculus, mouse, receptor tyrosine-protein kinase erbB-4, proto-oncogene-like protein c-ErbB-4, Erbb4, Mer4,2.7.10.1

Components

Reagent (quantity): Assay Plate (1), Standard (2), Sample Diluent (1x20ml), Assay Diluent A (1x10ml), Assay Diluent B (1x10ml), Detection Reagent A (1×120µl), Detection B (1×120µl), Wash Buffer (25 x concentrate) (1 x 30 ml), Substrate (1 x 10 ml), Stop Solution (1 x 10 ml)

Gene Name: Erbb4

Sample volume: 100 μl

Sheet: Precoated

Restrictions: For research use only

Storage: 4 ° C / -20 ° C

Storage comment

Standard, Detection Reagent A, Detection Reagent B, and 96-well strip plate should be stored at -20 ° C upon receipt. The other reagents can be stored at 4 ° C.

Alternative name

Tyrosine receptor protein kinase erbB-4 (Summary of ERBB4 ELISA kit)

Synonyms

erbb4, si: ch211-227n20.1, Her4, c-erbB-4, HER4, p180erbB4, receptor tyrosine kinase 4 erb-b2, receptor tyrosine kinase 4a erb-b2, homolog 4 of the viral oncogene of erythroblastic leukemia v-erb- a (avian), erb-b2 receptor tyrosine kinase 4 L homeolog, ErbB-4 receptor tyrosine-protein kinase, ERBB4, erbb4a, erbb4, erbb4.L, Tsp_13582, Erbb4

Background

Synonyms: Erbb4, Mer4, mouse, Mus musculus, c-ErbB-4 protein of proto-oncogene type, tyrosine-receptor protein kinase erbB-4.

ERBB4 Rabbit pAb

A0750-200ul 200 ul
EUR 550.8

ERBB4 Rabbit pAb

A0750-20ul 20 ul Ask for price

ERBB4 Rabbit pAb

A0750-50ul 50 ul Ask for price

HER4 / ErbB4 Antibody

48301-100ul 100ul
EUR 399.6

HER4 / ErbB4 Antibody

48301-50ul 50ul
EUR 286.8

ERBB4 Rabbit pAb

A6133-100ul 100 ul
EUR 369.6

ERBB4 Rabbit pAb

A6133-200ul 200 ul
EUR 550.8

ERBB4 Rabbit pAb

A6133-20ul 20 ul
EUR 219.6

ERBB4 Rabbit pAb

A6133-50ul 50 ul
EUR 267.6

Anti-ERBB4 Antibody

A1862-100
EUR 483.6

ErbB4 Rabbit mAb

A19047-100ul 100 ul
EUR 492

ErbB4 Rabbit mAb

A19047-200ul 200 ul
EUR 685.2

ErbB4 Rabbit mAb

A19047-20ul 20 ul
EUR 265.2

ErbB4 Rabbit mAb

A19047-50ul 50 ul
EUR 344.4

ERBB4 (pY1284) Antibody

abx333471-100ul 100 ul
EUR 560.4

ERBB4 Antibody (HRP)

20-abx314128
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

ERBB4 Antibody (FITC)

20-abx314129
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

ERBB4 Antibody (Biotin)

20-abx314130
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

ERBB4 Conjugated Antibody

C35681 100ul
EUR 476.4

ERBB4 cloning plasmid

CSB-CL624020HU-10ug 10ug
EUR 1653.6
Description: A cloning plasmid for the ERBB4 gene.

ERBB4 Conjugated Antibody

C43833 100ul
EUR 476.4

Anti-ERBB4 antibody

PAab02829 100 ug
EUR 463.2

anti- ERBB4 antibody

FNab02829 100µg
EUR 658.5
Description: Antibody raised against ERBB4

Anti-ERBB4 antibody

STJ111021 100 µl
EUR 332.4
Description: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Anti-ERBB4 Antibody

STJ501323 100 µg
EUR 571.2

Anti-ERBB4 antibody

STJ27886 100 µl
EUR 332.4
Description: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Anti-ERBB4 antibody

STJ23560 100 µl
EUR 332.4
Description: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

ERBB4 Antibody (HER4)

R30981 100 ug
EUR 419

ERBB4 Antibody / HER4

RQ4013 100 ug
EUR 419

ERBB4 Antibody (HER4)

F50604-0.08ML 0.08 ml
EUR 165

ERBB4 Antibody (HER4)

F50605-0.08ML 0.08 ml
EUR 165

ERBB4 Antibody (HER4)

F53135-0.08ML 0.08 ml
EUR 165

ERBB4 Antibody (HER4)

F40046-0.08ML 0.08 ml
EUR 165

ERBB4 Antibody / HER4

V7740-100UG 100 ug
EUR 499
Description: The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. The gene encoding ErbB-4 is expressed as a full-length protein, which produces a short membrane-anchored cytoplasmic domain fragment and a long ectodomain fragment. The short fragment is heavily tyrosine phosphorylated and possesses tyrosine kinase catalytic activity toward an exogenous substrate. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum. Its expression in breast cancer, pediatric brain cancer and other types of carcinomas has been reported in studies which suggest ErbB4 expression is involved in both normal tissue development and carcinogenesis.

ERBB4 Antibody / HER4

V7740-20UG 20 ug
EUR 219
Description: The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. The gene encoding ErbB-4 is expressed as a full-length protein, which produces a short membrane-anchored cytoplasmic domain fragment and a long ectodomain fragment. The short fragment is heavily tyrosine phosphorylated and possesses tyrosine kinase catalytic activity toward an exogenous substrate. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum. Its expression in breast cancer, pediatric brain cancer and other types of carcinomas has been reported in studies which suggest ErbB4 expression is involved in both normal tissue development and carcinogenesis.

ERBB4 Antibody / HER4

V7740SAF-100UG 100 ug
EUR 499
Description: The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. The gene encoding ErbB-4 is expressed as a full-length protein, which produces a short membrane-anchored cytoplasmic domain fragment and a long ectodomain fragment. The short fragment is heavily tyrosine phosphorylated and possesses tyrosine kinase catalytic activity toward an exogenous substrate. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum. Its expression in breast cancer, pediatric brain cancer and other types of carcinomas has been reported in studies which suggest ErbB4 expression is involved in both normal tissue development and carcinogenesis.

ERBB4 Antibody / HER4

V7741-100UG 100 ug
EUR 499
Description: The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. The gene encoding ErbB-4 is expressed as a full-length protein, which produces a short membrane-anchored cytoplasmic domain fragment and a long ectodomain fragment. The short fragment is heavily tyrosine phosphorylated and possesses tyrosine kinase catalytic activity toward an exogenous substrate. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum. Its expression in breast cancer, pediatric brain cancer and other types of carcinomas has been reported in studies which suggest ErbB4 expression is involved in both normal tissue development and carcinogenesis.

ERBB4 Antibody / HER4

V7741-20UG 20 ug
EUR 219
Description: The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. The gene encoding ErbB-4 is expressed as a full-length protein, which produces a short membrane-anchored cytoplasmic domain fragment and a long ectodomain fragment. The short fragment is heavily tyrosine phosphorylated and possesses tyrosine kinase catalytic activity toward an exogenous substrate. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum. Its expression in breast cancer, pediatric brain cancer and other types of carcinomas has been reported in studies which suggest ErbB4 expression is involved in both normal tissue development and carcinogenesis.

ERBB4 Antibody / HER4

V7741SAF-100UG 100 ug
EUR 499
Description: The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. The gene encoding ErbB-4 is expressed as a full-length protein, which produces a short membrane-anchored cytoplasmic domain fragment and a long ectodomain fragment. The short fragment is heavily tyrosine phosphorylated and possesses tyrosine kinase catalytic activity toward an exogenous substrate. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum. Its expression in breast cancer, pediatric brain cancer and other types of carcinomas has been reported in studies which suggest ErbB4 expression is involved in both normal tissue development and carcinogenesis.

Erbb4 sgRNA CRISPR Lentivector set (Mouse)

K3844101 3 x 1.0 ug
EUR 406.8

Human ERBB4 shRNA Plasmid

20-abx951441
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Phospho-ERBB4 (Tyr1284) Antibody

CSB-PA696402-
EUR 402
Description: A polyclonal antibody against Phospho-ERBB4 (Tyr1284). Recognizes Phospho-ERBB4 (Tyr1284) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-ERBB4 (Tyr1284) Antibody

CSB-PA696402-100ul 100ul
EUR 434.4
Description: A polyclonal antibody against Phospho-ERBB4 (Tyr1284). Recognizes Phospho-ERBB4 (Tyr1284) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

HER4 / ErbB4 Conjugated Antibody

C48301 100ul
EUR 476.4

HER4/ErbB4 Blocking Peptide

AF4775-BP 1mg
EUR 234

Rat ERBB4 shRNA Plasmid

20-abx986000
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

ERBB4 Antibody, HRP conjugated

1-CSB-PA007766LB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ERBB4. Recognizes ERBB4 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

ERBB4 Antibody, FITC conjugated

1-CSB-PA007766LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ERBB4. Recognizes ERBB4 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

ERBB4 Antibody, Biotin conjugated

1-CSB-PA007766LD01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ERBB4. Recognizes ERBB4 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Phospho-ERBB4 (Y1284) Antibody

1-CSB-PA008113
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-ERBB4 (Y1284). Recognizes Phospho-ERBB4 (Y1284) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/10000

ERBB4 ELISA KIT|Human

EF009427 96 Tests
EUR 826.8

Antibody for Human ErbB4

SPC-1139D 0.1ml
EUR 424.8
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is unconjugated.

Antibody for Human ErbB4

SPC-1139D-A390 0.1ml
EUR 481.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 390.

Antibody for Human ErbB4

SPC-1139D-A488 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 488.

Antibody for Human ErbB4

SPC-1139D-A565 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 565.

Antibody for Human ErbB4

SPC-1139D-A594 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 594.

Antibody for Human ErbB4

SPC-1139D-A633 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 633.

Antibody for Human ErbB4

SPC-1139D-A655 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 655.

Antibody for Human ErbB4

SPC-1139D-A680 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 680.

Antibody for Human ErbB4

SPC-1139D-A700 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 700.

Antibody for Human ErbB4

SPC-1139D-ALP 0.1ml
EUR 472.8
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Alkaline Phosphatase.

Antibody for Human ErbB4

SPC-1139D-APC 0.1ml
EUR 478.8
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to APC .

Antibody for Human ErbB4

SPC-1139D-APCCY7 0.1ml
EUR 565.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to APC/Cy7.

Antibody for Human ErbB4

SPC-1139D-BI 0.1ml
EUR 475.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Biotin.

Antibody for Human ErbB4

SPC-1139D-DY350 0.1ml
EUR 570
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 350.

Antibody for Human ErbB4

SPC-1139D-DY405 0.1ml
EUR 542.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 405.

Antibody for Human ErbB4

SPC-1139D-DY488 0.1ml
EUR 518.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 488.

Antibody for Human ErbB4

SPC-1139D-DY594 0.1ml
EUR 523.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 594.

Antibody for Human ErbB4

SPC-1139D-DY633 0.1ml
EUR 511.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 633.

Antibody for Human ErbB4

SPC-1139D-FITC 0.1ml
EUR 470.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to FITC.

Antibody for Human ErbB4

SPC-1139D-HRP 0.1ml
EUR 465.6
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to HRP.

Antibody for Human ErbB4

SPC-1139D-P594 0.1ml
EUR 488.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to PE/ATTO 594.

Antibody for Human ErbB4

SPC-1139D-PCP 0.1ml
EUR 478.8
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to PerCP.

Antibody for Human ErbB4

SPC-1139D-RPE 0.1ml
EUR 476.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to RPE .

Antibody for Human ErbB4

SPC-1139D-STR 0.1ml
EUR 477.6
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA42-56). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Streptavidin.

Antibody for Human ErbB4

SPC-1140D 0.1ml
EUR 424.8
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is unconjugated.

Antibody for Human ErbB4

SPC-1140D-A390 0.1ml
EUR 481.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 390.

Antibody for Human ErbB4

SPC-1140D-A488 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 488.

Antibody for Human ErbB4

SPC-1140D-A565 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 565.

Antibody for Human ErbB4

SPC-1140D-A594 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 594.

Antibody for Human ErbB4

SPC-1140D-A633 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 633.

Antibody for Human ErbB4

SPC-1140D-A655 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 655.

Antibody for Human ErbB4

SPC-1140D-A680 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 680.

Antibody for Human ErbB4

SPC-1140D-A700 0.1ml
EUR 480
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to ATTO 700.

Antibody for Human ErbB4

SPC-1140D-ALP 0.1ml
EUR 472.8
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Alkaline Phosphatase.

Antibody for Human ErbB4

SPC-1140D-APC 0.1ml
EUR 478.8
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to APC .

Antibody for Human ErbB4

SPC-1140D-APCCY7 0.1ml
EUR 565.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to APC/Cy7.

Antibody for Human ErbB4

SPC-1140D-BI 0.1ml
EUR 475.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Biotin.

Antibody for Human ErbB4

SPC-1140D-DY350 0.1ml
EUR 570
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 350.

Antibody for Human ErbB4

SPC-1140D-DY405 0.1ml
EUR 542.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 405.

Antibody for Human ErbB4

SPC-1140D-DY488 0.1ml
EUR 518.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 488.

Antibody for Human ErbB4

SPC-1140D-DY594 0.1ml
EUR 523.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 594.

Antibody for Human ErbB4

SPC-1140D-DY633 0.1ml
EUR 511.2
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Dylight 633.

Antibody for Human ErbB4

SPC-1140D-FITC 0.1ml
EUR 470.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to FITC.

Antibody for Human ErbB4

SPC-1140D-HRP 0.1ml
EUR 465.6
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to HRP.

Antibody for Human ErbB4

SPC-1140D-P594 0.1ml
EUR 488.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to PE/ATTO 594.

Antibody for Human ErbB4

SPC-1140D-PCP 0.1ml
EUR 478.8
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to PerCP.

Antibody for Human ErbB4

SPC-1140D-RPE 0.1ml
EUR 476.4
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to RPE .

Antibody for Human ErbB4

SPC-1140D-STR 0.1ml
EUR 477.6
Description: A polyclonal antibody for ErbB4 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide of human ErbB4 (AA1283-1296). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This ErbB4 antibody is conjugated to Streptavidin.

Anti-ERBB4 Antibody (Biotin)

STJ501326 100 µg
EUR 703.2

Anti-ERBB4 Antibody (FITC)

STJ501327 100 µg
EUR 703.2

ERBB4 Antibody (phospho-Y1162)

F48403-0.08ML 0.08 ml
EUR 165

Phospho-ERBB4 Antibody (pY1162)

F48403-0.4ML 0.4 ml
EUR 389

ERBB4 Antibody (phospho-Y1188)

F48404-0.08ML 0.08 ml
EUR 165

Erbb4 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3844102 1.0 ug DNA
EUR 184.8

Erbb4 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3844103 1.0 ug DNA
EUR 184.8

Erbb4 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3844104 1.0 ug DNA
EUR 184.8

ERBB4 Protein Vector (Mouse) (pPB-C-His)

PV176142 500 ng
EUR 1278

ERBB4 Protein Vector (Mouse) (pPB-N-His)

PV176143 500 ng
EUR 1278

ERBB4 Protein Vector (Mouse) (pPM-C-HA)

PV176144 500 ng
EUR 1278

ERBB4 Protein Vector (Mouse) (pPM-C-His)

PV176145 500 ng
EUR 1278

Recombinant Mouse ErbB4 Protein (aa 1-652) [His]

VAng-Cr3997-100g 100 µg
EUR 2024.4
Description: Recombinant Mouse ErbB4 Protein (Met1-Leu652) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 71.5 kDa. (Accession ID: Q99P91)

Recombinant Mouse ErbB4 Protein (aa 1-652) [His]

VAng-Cr3997-50g 50 µg
EUR 1232.4
Description: Recombinant Mouse ErbB4 Protein (Met1-Leu652) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 71.5 kDa. (Accession ID: Q99P91)

Phospho- HER4/ErbB4 (Tyr984) Antibody

ABF3609 100 ug
EUR 525.6

Anti-ErbB 4/ERBB4 Antibody

A00296 100ug/vial
EUR 400.8

Polyclonal ERBB4 / HER4 Antibody (Internal)

APR01999G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ERBB4 / HER4 (Internal). This antibody is tested and proven to work in the following applications:

Polyclonal ERBB4 / HER4 Antibody (Internal)

APR02023G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ERBB4 / HER4 (Internal). This antibody is tested and proven to work in the following applications:

Monoclonal ERBB4 Antibody, Clone: 5G6B4

AMM03025G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human ERBB4. The antibodies are raised in Mouse and are from clone 5G6B4. This antibody is applicable in WB and IHC, FC, ICC, E

Polyclonal ERBB4 Antibody(N-term)

APR05969G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ERBB4 (N-term). This antibody is tested and proven to work in the following applications:

Polyclonal ERBB4 Antibody(C-term)

APR05970G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ERBB4 (C-term). This antibody is tested and proven to work in the following applications:

Phospho-ERBB4-Y1284 Rabbit pAb

AP0034-100ul 100 ul
EUR 460.8

Phospho-ERBB4-Y1284 Rabbit pAb

AP0034-200ul 200 ul
EUR 664.8

Phospho-ERBB4-Y1284 Rabbit pAb

AP0034-20ul 20 ul
EUR 219.6

Phospho-ERBB4-Y1284 Rabbit pAb

AP0034-50ul 50 ul
EUR 318

ERBB4 ELISA Kit (Human) (OKAN06159)

OKAN06159 96 Wells
EUR 950.4
Description: Description of target: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.062 ng/mL

Erbb4 ORF Vector (Rat) (pORF)

ORF066618 1.0 ug DNA
EUR 607.2

ERBB4 ELISA Kit (Rat) (OKEH08781)

OKEH08781 96 Wells
EUR 1075.2
Description: Description of target: binds neuregulins; involved in epithelial-mesenchymal interactions during development; may play a role in tooth morphogenesis [RGD, Feb 2006];Species reactivity: Rat;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.294ng/mL

ERBB4 ORF Vector (Human) (pORF)

ORF018952 1.0 ug DNA
EUR 486

ErbB4 ELISA Kit (Human) (OKDD00255)

OKDD00255 96 Wells
EUR 1170
Description: Description of target: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.;Species reactivity: Human;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: < 0.062 ng/mL

ERBB4 ELISA Kit (Human) (OKCD00310)

OKCD00310 96 Wells
EUR 997.2
Description: Description of target: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required for normal cardiac muscle differentiation during embryonic development, and for postnatal cardiomyocyte proliferation. Required for normal development of the embryonic central nervous system, especially for normal neural crest cell migration and normal axon guidance. Required for mammary gland differentiation, induction of milk proteins and lactation. Acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors. Ligand specificity and signaling is modulated by alternative splicing, proteolytic processing, and by the formation of heterodimers with other ERBB family members, thereby creating multiple combinations of intracellular phosphotyrosines that trigger ligand- and context-specific cellular responses. Mediates phosphorylation of SHC1 and activation of the MAP kinases MAPK1/ERK2 and MAPK3/ERK1. Isoform JM-A CYT-1 and isoform JM-B CYT-1 phosphorylate PIK3R1, leading to the activation of phosphatidylinositol 3-kinase and AKT1 and protect cells against apoptosis. Isoform JM-A CYT-1 and isoform JM-B CYT-1 mediate reorganization of the actin cytoskeleton and promote cell migration in response to NRG1. Isoform JM-A CYT-2 and isoform JM-B CYT-2 lack the phosphotyrosine that mediates interaction with PIK3R1, and hence do not phosphorylate PIK3R1, do not protect cells against apoptosis, and do not promote reorganization of the actin cytoskeleton and cell migration. Proteolytic processing of isoform JM-A CYT-1 and isoform JM-A CYT-2 gives rise to the corresponding soluble intracellular domains (4ICD) that translocate to the nucleus, promote nuclear import of STAT5A, activation of STAT5A, mammary epithelium differentiation, cell proliferation and activation of gene expression. The ERBB4 soluble intracellular domains (4ICD) colocalize with STAT5A at the CSN2 promoter to regulate transcription of milk proteins during lactation. The ERBB4 soluble intracellular domains can also translocate to mitochondria and promote apoptosis.22 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.1"Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family."_x005F_x005F_x000D_Plowman G.D., Culouscou J.-M., Whitney G.S., Green J.M., Carlton G.W., Foy L., Neubauer M.G., Shoyab M._x005F_x005F_x000D_Proc. Natl. Acad. Sci. U.S.A. 90:1746-1750(1993) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM JM-A CYT-1), FUNCTION AS CELL SURFACE RECEPTOR, AUTOPHOSPHORYLATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.Ref.2"A novel juxtamembrane domain isoform of HER4/ErbB4. Isoform-specific tissue distribution and differential processing in response to phorbol ester."_x005F_x005F_x000D_Elenius K., Corfas G., Paul S., Choi C.J., Rio C., Plowman G.D., Klagsbrun M._x005F_x005F_x000D_J. Biol. Chem. 272:26761-26768(1997) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS JM-A CYT-1 AND JM-B CYT-1), TISSUE SPECIFICITY, FUNCTION AS CELL SURFACE RECEPTOR FOR NRG1 AND BTC, SUBCELLULAR LOCATION, AUTOPHOSPHORYLATION, PROTEOLYTIC PROCESSING.Ref.7"HER4-mediated biological and biochemical properties in NIH 3T3 cells. Evidence for HER1-HER4 heterodimers."_x005F_x005F_x000D_Cohen B.D., Green J.M., Foy L., Fell H.P._x005F_x005F_x000D_J. Biol. Chem. 271:4813-4818(1996) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS NRG1 RECEPTOR IN REGULATION OF CELL PROLIFERATION, CATALYTIC ACTIVITY, ENZYME REGULATION, AUTOPHOSPHORYLATION, PHOSPHORYLATION AT TYR-1056; TYR-1188 AND TYR-1242, INTERACTION WITH EGFR; SHC1 AND PIK3R1.Ref.9"Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation."_x005F_x005F_x000D_Elenius K., Paul S., Allison G., Sun J., Klagsbrun M._x005F_x005F_x000D_EMBO J. 16:1268-1278(1997) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS HBEGF RECEPTOR; IN CELL MIGRATION; CELL PROLIFERATION AND IN ACTIVATION OF PIK3R1, INTERACTION WITH HBEGF AND PIK3R1, AUTOPHOSPHORYLATION.Ref.10"Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases."_x005F_x005F_x000D_Carraway K.L. III, Weber J.L., Unger M.J., Ledesma J., Yu N., Gassmann M., Lai C._x005F_x005F_x000D_Nature 387:512-516(1997) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH NRG2, FUNCTION AS NRG2 RECEPTOR, PHOSPHORYLATION.Ref.14"ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases."_x005F_x005F_x000D_Olayioye M.A., Beuvink I., Horsch K., Daly J.M., Hynes N.E._x005F_x005F_x000D_J. Biol. Chem. 274:17209-17218(1999) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH ERBB2, FUNCTION IN ACTIVATION OF STAT5A.Ref.15"Characterization of a naturally occurring ErbB4 isoform that does not bind or activate phosphatidyl inositol 3-kinase."_x005F_x005F_x000D_Elenius K., Choi C.J., Paul S., Santiestevan E., Nishi E., Klagsbrun M._x005F_x005F_x000D_Oncogene 18:2607-2615(1999) [PubMed] [Europe PMC] [Abstract]Cited for: ALTERNATIVE SPLICING, FUNCTION IN PHOSPHORYLATION AND ACTIVATION OF PIK3R1, INTERACTION WITH NRG1 AND PIKR3R1, AUTOPHOSPHORYLATION, TISSUE SPECIFICITY.Ref.16"Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase."_x005F_x005F_x000D_Harari D., Tzahar E., Romano J., Shelly M., Pierce J.H., Andrews G.C., Yarden Y._x005F_x005F_x000D_Oncogene 18:2681-2689(1999) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS NRG4 RECEPTOR IN ACTIVATION OF MAPK1/ERK2 AND MAPK3/ERK1 AND IN CELL PROLIFERATION, INTERACTION WITH NRG4, SUBCELLULAR LOCATION.Ref.17"A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis."_x005F_x005F_x000D_Kainulainen V., Sundvall M., Maatta J.A., Santiestevan E., Klagsbrun M., Elenius K._x005F_x005F_x000D_J. Biol. Chem. 275:8641-8649(2000) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS NRG1 RECEPTOR IN CELL PROLIFERATION; MIGRATION; SURVIVAL AND IN PHOSPHORYLATION OF SHC1; ACTIVATION OF MAPK1/ERK2 AND MAPK3/ERK1, ALTERNATIVE SPLICING.Ref.19"Ligand discrimination in signaling through an ErbB4 receptor homodimer."_x005F_x005F_x000D_Sweeney C., Lai C., Riese D.J. II, Diamonti A.J., Cantley L.C., Carraway K.L. III_x005F_x005F_x000D_J. Biol. Chem. 275:19803-19807(2000) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN ACTIVATION OF AKT1; MAPK1/ERK2 AND MAPK3/ERK1, INTERACTION WITH PIK3R1; GRB2; SHC1; BTC; NRG1; NRG2 AND NRG3, LIGAND-SPECIFIC AUTOPHOSPHORYLATION.Ref.21"BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells."_x005F_x005F_x000D_Egeblad M., Mortensen O.H., van Kempen L.C., Jaattela M._x005F_x005F_x000D_Biochem. Biophys. Res. Commun. 281:25-31(2001) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS NRG1 RECEPTOR AND IN ACTIVATION OF MAP KINASES, AUTOPHOSPHORYLATION, ENZYME REGULATION.Ref.22"Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells."_x005F_x005F_x000D_Sartor C.I., Zhou H., Kozlowska E., Guttridge K., Kawata E., Caskey L., Harrelson J., Hynes N., Ethier S., Calvo B., Earp H.S. III_x005F_x005F_x000D_Mol. Cell. Biol. 21:4265-4275(2001) [PubMed] [Europe PMC] [Abstract]Cited for: MUTAGENESIS OF LYS-751, FUNCTION IN PROMOTING CELL DIFFERENTIATION AND INHIBITING CELL PROLIFERATION.Ref.23"WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus."_x005F_x005F_x000D_Komuro A., Nagai M., Navin N.E., Sudol M._x005F_x005F_x000D_J. Biol. Chem. 278:33334-33341(2003) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, PROTEOLYTIC PROCESSING, SUBCELLULAR LOCATION, INTERACTION WITH YAP1, MUTAGENESIS OF TYR-1301.Ref.25"The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone."_x005F_x005F_x000D_Williams C.C., Allison J.G., Vidal G.A., Burow M.E., Beckman B.S., Marrero L., Jones F.E._x005F_x005F_x000D_J. Cell Biol. 167:469-478(2004) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH STAT5A, SUBCELLULAR LOCATION, FUNCTION IN NUCLEAR LOCALIZATION OF STAT5A; DNA-BINDING, MUTAGENESIS OF 681-LYS--ARG-684.Ref.27"Presenilin-dependent gamma-secretase processing regulates multiple ERBB4/HER4 activities."_x005F_x005F_x000D_Vidal G.A., Naresh A., Marrero L., Jones F.E._x005F_x005F_x000D_J. Biol. Chem. 280:19777-19783(2005) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, PROTEOLYTIC PROCESSING, MUTAGENESIS OF VAL-675.Ref.28"The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells."_x005F_x005F_x000D_Naresh A., Long W., Vidal G.A., Wimley W.C., Marrero L., Sartor C.I., Tovey S., Cooke T.G., Bartlett J.M., Jones F.E._x005F_x005F_x000D_Cancer Res. 66:6412-6420(2006) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN PROMOTING APOPTOSIS, SUBCELLULAR LOCATION, INTERACTION WITH BCL2.Ref.30"Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth."_x005F_x005F_x000D_Maatta J.A., Sundvall M., Junttila T.T., Peri L., Laine V.J., Isola J., Egeblad M., Elenius K._x005F_x005F_x000D_Mol. Biol. Cell 17:67-79(2006) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, PHOSPHORYLATION, SUBCELLULAR LOCATION.Ref.31"The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells."_x005F_x005F_x000D_Muraoka-Cook R.S., Sandahl M., Husted C., Hunter D., Miraglia L., Feng S.M., Elenius K., Earp H.S. III_x005F_x005F_x000D_Mol. Biol. Cell 17:4118-4129(2006) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN DIFFERENTIATION OF MAMMARY EPITHELIUM, PROTEOLYTIC PROCESSING, AUTOPHOSPHORYLATION, SUBCELLULAR LOCATION, INTERACTION WITH STAT5A.Ref.33"HER4 D-box sequences regulate mitotic progression and degradation of the nuclear HER4 cleavage product s80HER4."_x005F_x005F_x000D_Strunk K.E., Husted C., Miraglia L.C., Sandahl M., Rearick W.A., Hunter D.M., Earp H.S. III, Muraoka-Cook R.S._x005F_x005F_x000D_Cancer Res. 67:6582-6590(2007) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION OF ERBB4 INTRACELLULAR DOMAIN, PROTEOLYTIC PROCESSING, SUBCELLULAR LOCATION, UBIQUITINATION OF ERBB4 INTRACELLULAR DOMAIN, MUTAGENESIS OF VAL-675; LYS-751; ARG-992; LEU-995 AND ASP-1000.Ref.35"Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains."_x005F_x005F_x000D_Sundvall M., Peri L., Maatta J.A., Tvorogov D., Paatero I., Savisalo M., Silvennoinen O., Yarden Y., Elenius K._x005F_x005F_x000D_Oncogene 26:6905-6914(2007) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION OF E4ICD, PHOSPHORYLATION, SUBCELLULAR LOCATION OF E4ICD, MUTAGENESIS OF LYS-751.Ref.38"Somatic mutations of ErbB4: selective loss-of-function phenotype affecting signal transduction pathways in cancer."_x005F_x005F_x000D_Tvorogov D., Sundvall M., Kurppa K., Hollmen M., Repo S., Johnson M.S., Elenius K._x005F_x005F_x000D_J. Biol. Chem. 284:5582-5591(2009) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN ACTIVATION OF SIGNALING PATHWAYS, INTERACTION WITH ERBB2, CATALYTIC ACTIVITY, AUTOPHOSPHORYLATION, PHOSPHORYLATION BY ERBB2, ENZYME REGULATION, MUTAGENESIS OF VAL-721; ALA-773; ARG-782; GLU-810; PRO-854; ASP-861; GLU-872 AND THR-926.Ref.40"Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways."_x005F_x005F_x000D_Gilmore-Hebert M., Ramabhadran R., Stern D.F._x005F_x005F_x000D_Mol. Cancer Res. 8:1388-1398(2010) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH TXNL4A; DDX23; MATR3; RBM15; ILF3; TRIM28; U5S1; U2SURP; ITCH; HNRPU; AP2A1; NULC; LEO1; WWP2; MDM2; HXK1 AND ARS2, FUNCTION, SUBCELLULAR LOCATION, IDENTIFICATION BY MASS SPECTROMETRY. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.062 ng/mL

Anti-ErbB 4/ERBB4 Antibody

PA1881 100ug/vial
EUR 352.8

Anti-Phospho-ERBB4-(Y1284) antibody

STJ22131 100 µl
EUR 471.6
Description: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Recombinant Human Her4/ErbB4 Protein

RP00120 10 μg
EUR 186

Phospho-HER4/ERBB4 Antibody (pY1188)

F48404-0.4ML 0.4 ml
EUR 389

Human CellExp? ErbB4/HER4, human recombinant

7401-10
EUR 294

Human CellExp? ErbB4/HER4, human recombinant

7401-50
EUR 836.4

ErbB4/HER4 (His Tagged), Human Recombinant

7773-5
EUR 314.4

Rabbit Anti Human Erbb4 Polyclonal Antibody

CPBT-65689RH 50 µg
EUR 1182

Phospho-HER4/ErbB4 (Tyr984) Blocking Peptide

AF4475-BP 1mg
EUR 234

Anti-ErbB4/Her4 Rabbit Monoclonal Antibody

M00296-1 100ug/vial
EUR 476.4
Description: Rabbit Monoclonal ErbB4/Her4 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Erbb4 sgRNA CRISPR Lentivector set (Rat)

K6785501 3 x 1.0 ug
EUR 406.8

ERBB4 sgRNA CRISPR Lentivector set (Human)

K0690701 3 x 1.0 ug
EUR 406.8

TranslationBlocker Human ErbB4/ Her4 siRNA, 10nmol

QX21-10nmol 10nmol
EUR 452.4

TranslationBlocker Human ErbB4/ Her4 siRNA, 2nmol

QX21-2nmol 2nmol
EUR 331.2

Mouse Receptor tyrosine-protein kinase erbB-4(ERBB4) ELISA kit

CSB-EL007766MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Receptor tyrosine-protein kinase erbB-4 (ERBB4) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Receptor tyrosine-protein kinase erbB-4(ERBB4) ELISA kit

1-CSB-EL007766MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Receptor tyrosine-protein kinase erbB-4(ERBB4) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Erbb4 ELISA Kit| Mouse Receptor tyrosine-protein kinase erbB-4

EF016491 96 Tests
EUR 826.8

Mouse Receptor tyrosine- protein kinase erbB- 4, Erbb4 ELISA KIT

ELI-08305m 96 Tests
EUR 1038

Erbb4 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3844105 3 x 1.0 ug
EUR 451.2

Erbb4 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6785502 1.0 ug DNA
EUR 184.8

Erbb4 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6785503 1.0 ug DNA
EUR 184.8

Erbb4 sgRNA CRISPR Lentivector (Rat) (Target 3)

K6785504 1.0 ug DNA
EUR 184.8

ERBB4 sgRNA CRISPR Lentivector (Human) (Target 1)

K0690702 1.0 ug DNA
EUR 184.8

ERBB4 sgRNA CRISPR Lentivector (Human) (Target 2)

K0690703 1.0 ug DNA
EUR 184.8

ERBB4 sgRNA CRISPR Lentivector (Human) (Target 3)

K0690704 1.0 ug DNA
EUR 184.8

Nori® Human Phospho-ErbB4 ELISA Kit

GR106279 96-well
EUR 553.2

ERBB4 Protein Vector (Human) (pPB-C-His)

PV075805 500 ng
EUR 973.2

ERBB4 Protein Vector (Human) (pPB-N-His)

PV075806 500 ng
EUR 973.2

ERBB4 Protein Vector (Human) (pPM-C-HA)

PV075807 500 ng
EUR 973.2

ERBB4 Protein Vector (Human) (pPM-C-His)

PV075808 500 ng
EUR 973.2

ERBB4 3'UTR Luciferase Stable Cell Line

TU006997 1.0 ml
EUR 5540.4

Erbb4 3'UTR GFP Stable Cell Line

TU254064 1.0 ml Ask for price

Erbb4 3'UTR Luciferase Stable Cell Line

TU105909 1.0 ml Ask for price

ERBB4 3'UTR GFP Stable Cell Line

TU056997 1.0 ml
EUR 5540.4

Erbb4 3'UTR Luciferase Stable Cell Line

TU204064 1.0 ml Ask for price

Erbb4 3'UTR GFP Stable Cell Line

TU155909 1.0 ml Ask for price

ERBB4 Protein Vector (Rat) (pPB-C-His)

PV266470 500 ng
EUR 1429.2

ERBB4 Protein Vector (Rat) (pPB-N-His)

PV266471 500 ng
EUR 1429.2

ERBB4 Protein Vector (Rat) (pPM-C-HA)

PV266472 500 ng
EUR 1429.2

ERBB4 Protein Vector (Rat) (pPM-C-His)

PV266473 500 ng
EUR 1429.2

Erbb4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3844106 1.0 ug DNA
EUR 200.4

Erbb4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3844107 1.0 ug DNA
EUR 200.4

Erbb4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3844108 1.0 ug DNA
EUR 200.4

Receptor Tyrosine-Protein Kinase ErbB-4 (ERBB4) Antibody

abx145647-100ug 100 ug
EUR 469.2

Receptor Tyrosine-Protein Kinase ErbB-4 (ERBB4) Antibody

abx146139-100ug 100 ug
EUR 469.2

Receptor Tyrosine-Protein Kinase ErbB-4 (ERBB4) Antibody

20-abx006809
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Receptor Tyrosine-Protein Kinase ErbB-4 (ERBB4) Antibody

20-abx116599
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Dodaj komentarz

Twój adres e-mail nie zostanie opublikowany. Wymagane pola są oznaczone *